RELISTOR Savings Program

Receive up to 7 FREE doses of RELISTOR

Salix Pharmaceuticals is proud to present the RELISTOR Co-pay Card. With this card, you will receive up to 7 free doses of RELISTOR and pay no more than $25 for all subsequent uses.*

RELISTOR Co-pay Card RELISTOR Co-pay Card

The co-pay portion of this program is not valid if your prescription plan is paid/partially paid by Medicaid, Medicare, federal or state government programs; however, you are eligible to participate in the free trial offer and receive 7 doses of RELISTOR at no cost to you.

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*Patient receives up to 7 doses at no cost to them and pays the initial $25 on all subsequent uses, with a maximum benefit of $100 for each use.

This card is valid for one use per month until 1/31/2014.

The co-pay portion of this program is not valid if your prescription plan is paid/partially paid by Medicaid, Medicare, federal or state government programs; however, you are eligible to participate in the free trial offer and receive 7 doses of RELISTOR at no cost to you.

Salix Pharmaceuticals reserves the right to rescind, revoke, or amend this offer without notice. Offer good only in the US. Void where prohibited by law.

Indication for RELISTOR

RELISTOR® is indicated for the treatment of opioid-induced constipation (OIC) in patients with advanced illness who are receiving palliative care, when response to laxative therapy has not been sufficient. Use of RELISTOR beyond four months has not been studied.

Important Safety Information about RELISTOR

Do not take RELISTOR® (methylnaltrexone bromide) Subcutaneous Injection if you have or may have a blockage in your intestines called a mechanical bowel obstruction. Symptoms of this blockage are vomiting, stomach pain, and swelling of your abdomen. Talk to your healthcare provider if you have any of these symptoms before taking RELISTOR.

Cases of holes or openings in your gastrointestinal (GI) tract have been reported in adult patients with opioid-induced constipation and advanced illness with certain conditions (i.e., cancer, peptic ulcer, Ogilvie's syndrome). These holes or openings have involved varying regions of the GI tract (e.g., stomach or intestines). Use RELISTOR with caution if you have a known or suspected wound or injury to the GI tract. If you get abdominal pain that is severe or will not go away, or nausea or vomiting that is new or worse, stop taking RELISTOR and call your healthcare provider.

If you get diarrhea that is severe or does not stop while taking RELISTOR, stop taking RELISTOR and call your healthcare provider.

Use of RELISTOR beyond four months has not been studied.

Safety and efficacy of RELISTOR have not been established in children.

The most common side effects of RELISTOR in clinical studies include: abdominal (stomach) pain, gas, nausea, dizziness, diarrhea, and sweating.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch/ or call 1-800-FDA-1088.

For product information, adverse event reports, and product complaint reports, please contact:

Salix Product Information Call Center
Phone: 1-800-508-0024
Fax: 1-510-595-8183
Email: salix@medcomsol.com

Please see complete Prescribing Information for RELISTOR.