RELISTOR Savings Program

Eligible patients may take advantage of a $0 copay on all of their RELISTOR prescriptions*

*Eligible patients may pay as little as $0 for their prescription. Eligible patients may receive a max benefit of $200 on their prescription. If patient’s initial out of pocket cost is greater than $200, the patient could be expected to pay more than $0. If the patient’s insurance does not cover the medication or the patient is paying cash, the patient will receive $200 off of the cost of the prescription. This offer is not valid in conjunction with a prescription plan that is paid/partially paid by Medicaid, Medicare, or federal or state government programs.

RELISTOR Co-pay Card RELISTOR Co-pay Card

Salix Pharmaceuticals reserves the right to rescind, revoke, or amend this offer without notice. Offer good only in the US. Void where
prohibited by law.

Indication for RELISTOR

RELISTOR® is indicated for the treatment of opioid-induced constipation (OIC) in patients with advanced illness who are receiving palliative care, when response to laxative therapy has not been sufficient. Use of RELISTOR beyond four months has not been studied.

Important Safety Information about RELISTOR

Do not take RELISTOR® (methylnaltrexone bromide) Subcutaneous Injection if you have or may have a blockage in your intestines called a mechanical bowel obstruction. Symptoms of this blockage are vomiting, stomach pain, and swelling of your abdomen. Talk to your healthcare provider if you have any of these symptoms before taking RELISTOR.

Cases of holes or openings in your gastrointestinal (GI) tract have been reported in adult patients with opioid-induced constipation and advanced illness with certain conditions (i.e., cancer, peptic ulcer, Ogilvie's syndrome). These holes or openings have involved varying regions of the GI tract (e.g., stomach or intestines). Use RELISTOR with caution if you have a known or suspected wound or injury to the GI tract. If you get abdominal pain that is severe or will not go away, or nausea or vomiting that is new or worse, stop taking RELISTOR and call your healthcare provider.

If you get diarrhea that is severe or does not stop while taking RELISTOR, stop taking RELISTOR and call your healthcare provider.

Use of RELISTOR beyond four months has not been studied.

Safety and efficacy of RELISTOR have not been established in children.

The most common side effects of RELISTOR in clinical studies include: abdominal (stomach) pain, gas, nausea, dizziness, diarrhea, and sweating.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch/ or call 1-800-FDA-1088.

For product information, adverse event reports, and product complaint reports, please contact:

Salix Product Information Call Center
Phone: 1-800-508-0024
Fax: 1-510-595-8183
Email: customerservice@salix.com

Please see complete Prescribing Information for RELISTOR.