Helpful Websites

If you are living chronic non-cancer pain or with an advanced illness, it can be comforting to seek understanding and support from loved ones, healthcare professionals, and support groups.

The following list of helpful websites and other online resources can help. On these sites, you can learn about organizations where you can find more information and support. Some may have a local chapter in your area.

Chronic non-cancer pain

American Chronic Pain Association

The ACPA offers pain management tools as well as other helpful materials for individuals with chronic pain seeking to improve the quality of their lives.

The American Academy of Pain Medicine

AAPM offers helpful information to serve pain physicians who diagnose and treat pain patients as well as provides general information about pain.

National Fibromyalgia & Chronic Pain Association

The NFMCPA is an association that provides several resources on chronic pain, as well as a community resource to find support groups in your area.

American Pain Society

APS provides journals and other resources on pain management.

Advanced illness

American Cancer Society (ACS)

The ACS provides information about current cancer research, grants, and awards as well as information on national affairs, legislative updates, and community involvement. The ACS offers a wide range of patient education tools, such as treatment options and ways to stay healthy.

Food and Drug Administration (FDA)

The FDA provides information on foods and specific prescription drugs, safety alerts, recent product approvals, and more.

This website is sponsored by the Center to Advance Palliative Care (CAPC), a national organization dedicated to increasing the availability of palliative care services in hospitals and other healthcare settings. offers a wide range of information, including articles, news stories, videos, and a provider directory.

Hospice Association of America (HAA)

HAA is a national organization representing thousands of hospices, caregivers, and volunteers who serve terminally ill patients and their families.

Hospice Patients Alliance (HPA)

HPA provides information about hospice services; directly assists patients, families, and caregivers in resolving difficulties they may have with current hospice services; and promotes better quality hospice care throughout the United States.

Digestive health

American College of Gastroenterology (ACG)

ACG provides consumer guides on various gastroenterological disorders and common problems, offers digestive health tips, and has a physician locator to find an ACG member in your area.

American Gastroenterological Association (AGA)

The public section of this website offers a digestive health resource, a gastroenterologist locator service, and various helpful online links.

National Digestive Diseases Information Clearinghouse (NDDIC)

NDDIC offers free publications about digestive diseases to patients and a phone inquiry line to answer your questions about educational materials.

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIDDK provides information on various digestive diseases, health education programs, and clinical trials.


RELISTOR® is a prescription medicine used to treat constipation that is caused by prescription pain medicines called opioids, in adults:

  • with long-lasting (chronic) pain that is not caused by cancer.
  • receiving treatment for advanced illness, when other medicines for constipation have not worked well enough.
    • It is not known if RELISTOR is safe and effective if used for longer than 4 months in people with advanced illness.

Important Safety Information

Do not take RELISTOR® (methylnaltrexone bromide) Subcutaneous Injection if you have or may have a blockage in your intestines (called an intestinal obstruction) or a history of bowel blockage.

RELISTOR can cause serious side effects such as a tear in your stomach or intestinal wall (perforation). Stomach pain that is severe can be a sign of a serious medical condition. If you get stomach pain that does not go away, stop taking RELISTOR and get emergency medical help right away.

Stop using RELISTOR and call your healthcare provider if you get diarrhea that is severe or that does not go away during treatment with RELISTOR.

You may have symptoms of opioid withdrawal during treatment with RELISTOR including sweating, chills, diarrhea, stomach pain, anxiety, and yawning. Tell your healthcare provider if you have any of these symptoms.

Tell your healthcare provider if you have kidney problems or if you have any stomach or bowel (intestines) problems, including stomach ulcer, Crohn’s disease, diverticulitis, cancer of the stomach or bowel, or Ogilvie’s syndrome. Also, tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Tell your healthcare provider if you are pregnant or plan to become pregnant. Taking RELISTOR during pregnancy may cause opioid withdrawal symptoms in your unborn baby. Tell your healthcare provider right away if you become pregnant during treatment with RELISTOR. It is not known if RELISTOR passes into your breast milk. Taking RELISTOR while you are breastfeeding may cause opioid withdrawal in your baby. You and your healthcare provider should decide if you will take RELISTOR or breastfeed. You should not do both.

The most common side effects of RELISTOR in people with long-lasting (chronic) pain that is not caused by cancer include: stomach-area (abdomen) pain, nausea, diarrhea, sweating, hot flush, tremor, and chills.

The most common side effects of RELISTOR in people receiving treatment for their advanced illness include: stomach-area (abdomen) pain, gas, nausea, dizziness, and diarrhea.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

For product information, adverse event reports, and product complaint reports, please contact:

Salix Product Information Call Center
Phone: 1-800-508-0024
Fax: 1-510-595-8183

Click here for full Prescribing Information.

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