What is RELISTOR?

RELISTOR^® is a prescription medicine used to treat constipation in adults that is caused by prescription pain medicines called opioids.

RELISTOR tablets and RELISTOR injection are used to treat constipation caused by opioids in adults with long-lasting (chronic) pain that is not caused by active cancer.
RELISTOR injection is also used to treat constipation caused by opioids in adults with advanced illness or pain caused by active cancer and who need increases in their opioid dose for comfort care.

It is not known if RELISTOR is safe and effective in children.

You are not alone—many people who take opioids for long-lasting (chronic) pain may become constipated

40%-80% of patients taking opioids for long-lasting (chronic) pain may experience opioid-induced constipation (OIC)

How do you know if you have OIC? You may notice some of the following symptoms:

Not having bowel movements regularly (less than 3 per week)

Needing to push harder during a bowel movement

Dry, hard stools

Sense of incomplete emptying of your bowels

Bloating or pain in your stomach area

OIC can be frustrating and may impact your daily bowel routine.

Don’t suffer in silence. It’s time to talk to your healthcare provider if you’re experiencing any of these symptoms while taking an opioid, especially if you have tried over-the-counter (OTC) options

Download the OIC Healthcare Provider Discussion Guide.

Learn more about OTC laxatives and OIC

INDICATIONS

RELISTOR® is a prescription medicine used to treat constipation in adults that is caused by prescription pain medicines called opioids.

RELISTOR tablets and RELISTOR injection are used to treat constipation caused by opioids in adults with long-lasting (chronic) pain that is not caused by active cancer.

IMPORTANT SAFETY INFORMATION

Do not take RELISTOR if you have a bowel blockage (called an intestinal obstruction) or have a history of bowel blockage.
RELISTOR can cause serious side effects such as a tear in your stomach or intestinal wall (perforation). Stomach pain that is severe can be a sign of a serious medical condition. If you get stomach pain that is severe, does not go away, or gets worse, stop taking RELISTOR and get emergency medical help right away.

IMPORTANT SAFETY INFORMATION

Do not take RELISTOR if you have a bowel blockage (called an intestinal obstruction) or have a history of bowel blockage.
RELISTOR can cause serious side effects such as a tear in your stomach or intestinal wall (perforation). Stomach pain that is severe can be a sign of a serious medical condition. If you get stomach pain that is severe, does not go away, or gets worse, stop taking RELISTOR and get emergency medical help right away.